Khalid Al Mansoori

Neuropsychopharmacology Research

Ongoing Research & Studies

Selected research projects and clinical studies in neuropsychopharmacology, CNS mechanisms, and treatment modalities.

Insomnia Pharmacology & Treatment Landscape in the UAE

Year: 2026
Status: Published
Location: Dubai, UAE

A comprehensive clinical‑pharmacology review analyzing mechanisms of sleep regulation, pharmacological classes used for insomnia, and the availability of modern treatments including novel orexin antagonists within the UAE.

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Spravato (Esketamine) for Treatment-Resistant Depression

Duration: Jan – Mar 2026
Status: Ongoing
Location: Dubai, UAE

Clinical evaluation of Spravato (Esketamine), an NMDA receptor antagonist, in patients with major depressive disorder or treatment‑resistant depression who did not respond to standard therapies.

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Research Focus Areas

Sleep & Circadian Pharmacology

Sleep architecture, orexin signaling, hypnotic mechanisms, and circadian‑aligned interventions.

Mood Disorders & Treatment Resistance

Major depression mechanisms, NMDA receptor modulation, and novel antidepressant pathways.

Receptor Pharmacodynamics

Ligand‑receptor interactions, downstream signaling, and predictive receptor modeling.

Regional Clinical Applications

Evidence‑based healthcare in the UAE and Middle East region, treatment availability analysis.